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C4461
Sigma
Colistin sulfate salt
≥15,000 units/mg
| Synonym: | Polymyxin E |
| CAS Number: | 1264-72-8 |
| EC Number: | 215-034-3 |
| MDL number: | MFCD00146495 |
Description
| Biochem/physiol Actions | Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. |
Properties
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | TR1500000 |
References
| reference | David, H.L., and Rastogi, N., Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum. Antimicrob. Agents Chemother. 27, 701-707, (1985) |
| Evans, M.E., et al., Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant Gram-negative bacteria. Ann. Pharmacother. 33, 960-967, (1999) |
